Gesicles: Microvesicle "Cookies" for Transient Information Transfer Between Cells

被引:58
作者
Breakefield, Xandra O. [1 ,2 ,3 ,4 ]
Frederickson, Robert M. [5 ]
Simpson, Richard J. [6 ]
机构
[1] Massachusetts Gen Hosp, Ctr Neurosci, Boston, MA 02129 USA
[2] Massachusetts Gen Hosp, Dept Neurol, Mol Neurogenet Unit, Boston, MA 02114 USA
[3] Massachusetts Gen Hosp, Dept Radiol, Ctr Mol Imaging Res, Boston, MA 02114 USA
[4] Harvard Univ, Sch Med, Program Neurosci, Boston, MA 02115 USA
[5] Robert M Frederickson Consulting Inc, Seattle, WA USA
[6] La Trobe Univ, La Trobe Univ Inst Mol Sci LIMS, Bundoora, Vic, Australia
关键词
DIAGNOSTIC BIOMARKERS; EXOSOMES; CANCER; MECHANISM; DELIVERY; RNA;
D O I
10.1038/mt.2011.169
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 [微生物学]; 090105 [作物生产系统与生态工程];
摘要
引用
收藏
页码:1574 / 1576
页数:3
相关论文
共 22 条
[1]
Intercellular transfer of the oncogenic receptor EGFrvIII by microvesicles derived from tumour cells [J].
Al-Nedawi, Khalid ;
Meehan, Brian ;
Micallef, Johann ;
Lhotak, Vladimir ;
May, Linda ;
Guha, Abhijit ;
Rak, Janusz .
NATURE CELL BIOLOGY, 2008, 10 (05) :619-U24
[2]
Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes [J].
Alvarez-Erviti, Lydia ;
Seow, Yiqi ;
Yin, HaiFang ;
Betts, Corinne ;
Lakhal, Samira ;
Wood, Matthew J. A. .
NATURE BIOTECHNOLOGY, 2011, 29 (04) :341-U179
[3]
Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells [J].
Antonyak, Marc A. ;
Li, Bo ;
Boroughs, Lindsey K. ;
Johnson, Jared L. ;
Druso, Joseph E. ;
Bryant, Kirsten L. ;
Holowka, David A. ;
Cerione, Richard A. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (12) :4852-4857
[4]
Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences [J].
Balaj, Leonora ;
Lessard, Ryan ;
Dai, Lixin ;
Cho, Yoon-Jae ;
Pomeroy, Scott L. ;
Breakefield, Xandra O. ;
Skog, Johan .
NATURE COMMUNICATIONS, 2011, 2
[5]
Shedding microvesicles: artefacts no more [J].
Cocucci, Emanuele ;
Racchetti, Gabriella ;
Meldolesi, Jacopo .
TRENDS IN CELL BIOLOGY, 2009, 19 (02) :43-51
[6]
Detection of microRNA Expression in Human Peripheral Blood Microvesicles [J].
Hunter, Melissa Piper ;
Ismail, Noura ;
Zhang, Xiaoli ;
Aguda, Baltazar D. ;
Lee, Eun Joo ;
Yu, Lianbo ;
Xiao, Tao ;
Schafer, Jeffrey ;
Lee, Mei-Ling Ting ;
Schmittgen, Thomas D. ;
Nana-Sinkam, S. Patrick ;
Jarjoura, David ;
Marsh, Clay B. .
PLOS ONE, 2008, 3 (11)
[7]
Tumour-released exosomes and their implications in cancer immunity [J].
Iero, M. ;
Valenti, R. ;
Huber, V. ;
Filipazzi, P. ;
Parmiani, G. ;
Fais, S. ;
Rivoltini, L. .
CELL DEATH AND DIFFERENTIATION, 2008, 15 (01) :80-88
[8]
Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles:: A mechanism for cellular human immunodeficiency virus 1 infection [J].
Mack, M ;
Kleinschmidt, A ;
Brühl, H ;
Klier, C ;
Nelson, PJ ;
Cihak, J ;
Plachy, J ;
Stangassinger, M ;
Erfle, V ;
Schlöndorff, D .
NATURE MEDICINE, 2000, 6 (07) :769-+
[9]
MAGUIRE CA, 2011, MOL THER S1, V19, pS51
[10]
Protein Transfer Into Human Cells by VSV-G-induced Nanovesicles [J].
Mangeot, Philippe-Emmanuel ;
Dollet, Sandra ;
Girard, Mathilde ;
Ciancia, Claire ;
Joly, Stephane ;
Peschanski, Marc ;
Lotteau, Vincent .
MOLECULAR THERAPY, 2011, 19 (09) :1656-1666