ALTER: program-oriented conversion of DNA and protein alignments

被引:454
作者
Glez-Pena, Daniel [1 ]
Gomez-Blanco, Daniel [1 ]
Reboiro-Jato, Miguel [1 ]
Fdez-Riverola, Florentino [1 ]
Posada, David [2 ]
机构
[1] Univ Vigo, Dept Informat, Orense 32004, Spain
[2] Univ Vigo, Dept Bioquim Genet & Inmunol, Vigo 36310, Spain
基金
欧洲研究理事会;
关键词
MULTIPLE SEQUENCE ALIGNMENT; CLUSTAL-W; SELECTION; SOFTWARE;
D O I
10.1093/nar/gkq321
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
ALTER is an open web-based tool to transform between different multiple sequence alignment formats. The originality of ALTER lies in the fact that it focuses on the specifications of mainstream alignment and analysis programs rather than on the conversion among more or less specific formats. In addition, ALTER is capable of identify and remove identical sequences during the transformation process. Besides its user-friendly environment, ALTER allows access to its functionalities in a programmatic way through a Representational State Transfer web service. ALTER's front-end and its API are freely available at http://sing.ei.uvigo.es/ALTER/ and http://sing.ei.uvigo.es/ALTER/api/, respectively.
引用
收藏
页码:W14 / W18
页数:5
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