Remarkable hydrolysis of phosphodiester by neutral lanthanide(III) DO3A complexes

被引：14

作者：

Kalesse, M

Loos, A

机构：

[1] Institut für Organische Chemie, Universität Hannover, 30167 Hannover

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1996年 / 6卷 / 17期

关键词：

D O I：

10.1016/0960-894X(96)00386-1

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The hydrolysis of the 4-nitrophenyl phosphate ester of propylene glycol (HPNP) is catalyzed by neutral lanthanide(III) DO3A complexes. Hydrolysis experiments with complexes of modified ligands where the metal complex was positively charged did not yield in a significant increase of the rate constant. Copyright (C) 1996 Elsevier Science Ltd

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页码：2063 / 2068

页数：6

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