Turning green to gold

被引：117

作者：

McDonagh, AF ^{[1
]}

机构：

[1] Univ Calif San Francisco, Div Gastroenterol, San Francisco, CA 94143 USA

来源：

NATURE STRUCTURAL BIOLOGY | 2001年 / 8卷 / 03期

关键词：

D O I：

10.1038/84915

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Biliverdin is reduced to the potent antioxidant bilirubin in mammals and other vertebrates. The X-ray crystal structures of two biliverdin reductases, with different isomer specificities, show how substrate and cofactor bind to the enzymes and provide new insights into the mechanism of the reduction.

引用

页码：198 / 200

页数：3

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