Hereditary diffuse leucoencephalopathy with spheroids

被引：34

作者：

Hancock, N

Poon, M

Taylor, B

McLean, C

机构：

[1] Royal Hobart Hosp, Dept Gen Internal Med, Hobart, Tas 7001, Australia

[2] Western Hosp, Dept Neurol, Melbourne, Vic, Australia

[3] Royal Hobart Hosp, Dept Neurol, Hobart, Tas, Australia

[4] Univ Melbourne, Natl Hlth & Med Res Council, Dementia Brain Bank, Melbourne, Vic, Australia

[5] Monash Univ, Alfred Hosp, Melbourne, Vic 3181, Australia

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 2003年 / 74卷 / 09期

关键词：

D O I：

10.1136/jnnp.74.9.1345

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Hereditary diffuse leucoencephalopathy with spheroids (HDLS) is a rare inherited progressive leucoencephalopathy characterised by giant neuroaxonal swellings (spheroids) within the CNS white matter. The case is reported of a 45 year old woman with a rapidly progressive fulminant illness course characterised by progressive cognitive decline with depressive features. A presumed dominant inheritance pattern was elicited. This report reviews the literature on HDLS and the relation of this disorder to other conditions with giant neuroaxonal swellings.

引用

页码：1345 / 1347

页数：3

共 17 条

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