Control of intestinal inflammation by regulatory T cells

被引:51
作者
Toms, C [1 ]
Powrie, F [1 ]
机构
[1] Univ Oxford, Sir William Dunn Sch Pathol, Oxford OX1 3RE, England
关键词
immunity; mucosal; IL-10; TGF-beta;
D O I
10.1016/S1286-4579(01)01454-X
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Regulatory T(Treg)-cell populations have been identified in a number of disease models. In this review we focus on the role of naturally occurring Treg cells in the control of intestinal inflammation. Specifically, we discuss their mechanism of action with particular emphasis on the role of anti-inflammatory cytokines and cell surface molecules. (C) 2001 Editions scientifiques et medicales Elsevier SAS.
引用
收藏
页码:929 / 935
页数:7
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