Biotransformation of the fungistatic sesquiterpenoid ginsenol by Botrytis cinerea

被引：31

作者：

Aleu, J

Hernández-Galán, R

Hanson, JR

Hitchcock, PB

Collado, IG

机构：

[1] Univ Cadiz, Fac Ciencias, Dept Quim Organ, Cadiz 11510, Spain

[2] Univ Sussex, Sch Chem Phys & Environm Sci, Brighton BN1 9QJ, E Sussex, England

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1999年 / 06期

关键词：

D O I：

10.1039/a808044e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The antifungal properties of ginsenol (1) have been determined. The biotransformation of this fungistatic sesquiterpenoid by the plant pathogen Botrytis cinerea gave the 8- and 9-hydroxy derivatives (5 and 3) as the major metabolites and the 6 alpha- and 10 beta-hydroxy (8 and 7) and 8- and 9-oxo derivatives (6 and 4) as minor metabolites. The structure and stereochemistry of the major compound 3 were established by X-ray crystallography.

引用

页码：727 / 730

页数：4

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