Genetic diversity of cutaneous human papillomaviruses

被引:52
作者
Forslund, Ola [1 ]
机构
[1] Lund Univ, Univ Hosp MAS, Dept Lab Med, Div Med Microbiol, SE-20502 Malmo, Sweden
关键词
D O I
10.1099/vir.0.82911-0
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Human papillomaviruses (HPVs) of the genera Betapapillomavirus and Gammapapillomavirus are common on human skin. Sequencing of subgenomic amplicons of cutaneous HPVs has revealed a large number of novel putative HPV types within these genera. Phylogenetic analysis based on these amplicons revealed 133 putative HPV types with <90% sequence identity to any known HPV type or to each other. As there are already 34 characterized HPV types described within the genera Betapapillomavirus and Gammapapillomavirus, they appear to be the most genetically diverse of the HPVs, apparently comprising at least 167 different HPV types.
引用
收藏
页码:2662 / 2669
页数:8
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