Fungal metabolites.: Part 45:: The sesquiterpenes of Collybia maculata and Collybia peronata

被引：14

作者：

Castronovo, F

Clericuzio, M

Toma, L

Vidari, G

机构：

[1] Univ Pavia, Dipartimento Chim Organ, I-27100 Pavia, Italy

[2] Univ Turin, Dipartimento Chim Gen & Organ Appl, I-10125 Turin, Italy

来源：

TETRAHEDRON | 2001年 / 57卷 / 14期

关键词：

terpenes; fungi; molecular modelling; stereochemistry;

D O I：

10.1016/S0040-4020(01)00120-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The sesquiterpenes of Collybia maculata and C. peronata (Basidiomycetes) have been reinvestigated. In addition to collybolide, isocollybolide and deoxycollybulidol, five new structurally related sesquiterpene lactones have been isolated. The structures have been established by spectroscopic methods. Stereochemical assignments required a derailed conformational investigation, which has been carried out at the AM1 level fur all compounds, and at the B3LYP level for some of them. This led to the inversion of the previously proposed C-7 configuration of deoxycollybolidol. The absolute configuration of collybolides could tentatively be inferred from CD studies. (C) 2001 Elsevier Science Ltd. All rights reserved.

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页码：2791 / 2798

页数：8

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