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Susceptibility to lupus nephritis in the NZB/W model system

被引：55
作者：
Morel, L [1 ]
Wakeland, EK
机构：
[1] Univ Florida, Ctr Mammalian Genet, Gainesville, FL 32610 USA
[2] Univ Florida, Dept Immunol Pathol & Lab Med, Gainesville, FL 32610 USA
[3] Univ Texas, SW Med Ctr, Ctr Immunol, Dallas, TX 75235 USA
来源：
CURRENT OPINION IN IMMUNOLOGY | 1998年 / 10卷 / 06期
关键词：
D O I：
10.1016/S0952-7915(98)80094-0
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Advances in genetic mapping have resulted in the identification of multiple lupus susceptibility loci in the NZB/W mouse model. The analysis of congenic strains carrying these loci is now providing functional data on their role in lupus pathogenesis and is paving the way to the identification of the susceptibility genes and their molecular characterization.
引用
收藏
页码：718 / 725
页数：8
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