A rapid and precise on-response in posterior parietal cortex

被引:119
作者
Bisley, JW
Krishna, BS
Goldberg, ME
机构
[1] Columbia Univ Coll Phys & Surg, Ctr Neurobiol & Behav, Mahoney Ctr Brain & Behav, New York, NY 10032 USA
[2] New York State Psychiat Inst & Hosp, New York, NY 10032 USA
[3] Columbia Univ Coll Phys & Surg, Dept Neurol, New York, NY 10032 USA
[4] Columbia Univ Coll Phys & Surg, Dept Psychiat, New York, NY 10032 USA
关键词
neural coding; reliability; attention; parietal cortex; spike timing; vision;
D O I
10.1523/JNEUROSCI.5007-03.2004
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The activity of neurons in the lateral intraparietal area ( LIP) of the monkey predicts the monkey's allocation of spatial attention. We show here that despite being relatively high within the visual hierarchy, neurons in LIP have extremely short and precise visual latencies. Mean latency was 45.2 msec; the timing precision of the onset response was usually better than 4 msec. The majority of neurons had a pause in response after an initial burst, followed by more sustained visual activity. Previous attention allocation had no effect on either the latency or magnitude of the initial burst, but produced clear effects on the magnitude of the later sustained activity. Together, these data indicate that the initial burst in LIP visual response reflects an uncontaminated sensory signal. Information about stimulus onset is transmitted rapidly through the visual system to LIP; the on-response has a higher speed and temporal precision than realized previously. This information could be used to orient attention to novel objects in the visual environment rapidly and reliably.
引用
收藏
页码:1833 / 1838
页数:6
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