Behavioral symptoms after pallido-nigral lesions: A clinico-pathological case

被引：10

作者：

Adam, Julien ^{[2
]}

Baulac, Michel ^{[1
]}

Hauw, Jean-Jacques ^{[2
]}

Laplane, Dominique ^{[1
]}

Duyckaerts, Charles ^{[2
]}

机构：

[1] Hop La Pitie Salpetriere, Lab Neuropathol Escourolle R, F-75651 Paris 13, France

[2] Univ Paris 06, INSERM, Hop La Pitie Salpetriere, AP HP,Raymond Escourolle Neuropathol Lab,U679, Paris, France

来源：

NEUROCASE | 2008年 / 14卷 / 02期

关键词：

autoactivation deficit; basal ganglia; Alexander loop; substantia nigra; pallidum;

D O I：

10.1080/13554790802032200

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A 59-year-old patient presented with compulsive behaviors and lasting apathy after carbon monoxide intoxication. The apathy could be overcome by external stimulation (self-activation deficit). There was severe neuronal loss bilaterally in the anterior part of the pallidum and in the substantia nigra, pars reticulata. This first clinico-pathological case of a self-activation deficit illustrates the dissociation between motor and behavioral symptoms in lesions of the pallido-nigral complex, with the behavioral symptoms being related to lesions of the substantia nigra, pars reticulata and of the anterior part of the pallidum.

引用

页码：125 / 130

页数：6

共 11 条

[1]

ALEXANDER GE, 1990, PROG BRAIN RES, V85, P119

[2]

PARALLEL ORGANIZATION OF FUNCTIONALLY SEGREGATED CIRCUITS LINKING BASAL GANGLIA AND CORTEX [J].

ALEXANDER, GE ;

DELONG, MR ;

STRICK, PL .

ANNUAL REVIEW OF NEUROSCIENCE, 1986, 9 :357-381

[3]

Auer R. N., 2002, GREENFIELDS NEUROPAT

[4]

EDLING C, 1990, BRIT J IND MED, V47

[5]

FELDMAN RG, 1992, J CHILD NEUROLOGY, V7

[6]

HILLER F, 1924, Z GESAMTE NEUROLOGIE, V93

[7]

DYSTONIA AND AKINESIA DUE TO PALLIDOPUTAMINAL LESIONS AFTER DISULFIRAM INTOXICATION [J].

KRAUSS, JK ;

MOHADJER, M ;

WAKHLOO, AK ;

MUNDINGER, F .

MOVEMENT DISORDERS, 1991, 6 (02) :166-170

[8]

LESIONS OF BASAL GANGLIA DUE TO DISULFIRAM NEUROTOXICITY [J].

LAPLANE, D ;

ATTAL, N ;

SAURON, B ;

DEBILLY, A ;

DUBOIS, B .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1992, 55 (10) :925-929

[9]

PURE PSYCHIC AKINESIA WITH BILATERAL LESIONS OF BASAL GANGLIA [J].

LAPLANE, D ;

BAULAC, M ;

WIDLOCHER, D ;

DUBOIS, B .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1984, 47 (04) :377-385

[10]

OBSESSIVE-COMPULSIVE AND OTHER BEHAVIORAL-CHANGES WITH BILATERAL BASAL GANGLIA LESIONS - A NEUROPSYCHOLOGICAL, MAGNETIC-RESONANCE IMAGING AND POSITRON TOMOGRAPHY STUDY [J].

LAPLANE, D ;

LEVASSEUR, M ;

PILLON, B ;

DUBOIS, B ;

BAULAC, M ;

MAZOYER, B ;

DINH, ST ;

SETTE, G ;

DANZE, F ;

BARON, JC .

BRAIN, 1989, 112 :699-725

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