Advances in fluorescence in situ hybridization

被引：48

作者：

Raap, AK ^{[1
]}

机构：

[1] Leiden State Univ, Med Ctr, Dept Mol Cell Biol, Lab Cytochem & Cytometry, NL-2333 AL Leiden, Netherlands

来源：

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS | 1998年 / 400卷 / 1-2期

关键词：

molecular cytogenetics; FISH; Fiber-FISH; Multicolour-FISH; CGH; tyramide; padlock probe; polypeptide nucleic acid;

D O I：

10.1016/S0027-5107(98)00029-3

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The techniques of in situ hybridization (ISH) are widely applied for analyzing the genetic make-up and RNA expression patterns of individual cells. This review focusses on a number of advances made over the last 5 years in the fluorescence ISH (FISH) field, i.e., Fiber-FISH, Multi-colour chromosome painting, Comparative Genomic Hybridization, Tyramide Signal Amplification and FISH with Polypeptide Nucleic Acid and Padlock probes. (C) 1998 Elsevier Science B.V. All rights reserved.

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收藏

页码：287 / 298

页数：12

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