Vanadyl triflate as an efficient and recyclable catalyst for the synthesis of α-aminonitriles

被引：20

作者：

De, SK

机构：

[1] Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy, Purdue University, West Lafayette

来源：

SYNTHETIC COMMUNICATIONS | 2005年 / 35卷 / 12期

关键词：

alpha-aminonitriles; aldehydes; amines; recyclability; trimethylsilyl cyanide; vanadyl triflate;

D O I：

10.1081/SCC-200061547

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Vanadyl triflate to catalyzed Strecker-type reactions were successfully carried out by simply mixing aldehydes, amines, and trimethylsilyl cyanide at room temperature to afford alpha-aminonitriles in good yields.

引用

页码：1577 / 1582

页数：6

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