What is new in the prevention of ventilator-associated pneumonia?

被引:18
作者
Blot, Stijn [1 ]
Rello, Jordi [2 ]
Vogelaers, Dirk [1 ]
机构
[1] Ghent Univ Hosp, B-9000 Ghent, Belgium
[2] Univ Autonoma Barcelona, Hosp Univ Vall dHebron, Vall DHebron Inst Res, CIBERES, E-08193 Barcelona, Spain
关键词
bundle; endotracheal tube; prevention; ventilator-associated pneumonia; INTENSIVE-CARE UNITS; SUBGLOTTIC SECRETION DRAINAGE; EVIDENCE-BASED GUIDELINES; TUBE CUFF PRESSURE; NOSOCOMIAL INFECTION; ENDOTRACHEAL-TUBE; RANDOMIZED-TRIAL; KNOWLEDGE TEST; PROGRAM; NURSES;
D O I
10.1097/MCP.0b013e328344db65
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
100201 [内科学];
摘要
Purpose of review Ventilator-associated pneumonia (VAP) remains a frequent and severe complication in endotracheally intubated patients. Strict adherence to preventive measures reduces the risk of VAP. The objective of this paper is to review what has come forward in recent years in the nonpharmacological prevention of VAP. Recent findings It seems advantageous to implement care bundles rather than single prevention measures. A solid basis of knowledge seems necessary to facilitate implementation and maintain a high adherence level. Continuous educational efforts have a beneficial effect on attitude toward VAP. Intermittent subglottic secretions drainage, continuous lateral rotation therapy, and polyurethane cuffed endotracheal tubes decrease the risk of pneumonia. In an in-vitro setting, an endotracheal tube with a taper-shaped cuff appears to better prevent fluid leakage compared to cylindrical polyurethane or polyvinylchloride cuffed tubes. Cuff pressure control by means of an automatic device and multimodality chest physiotherapy need further investigation, as do some aspects of oral hygiene. Summary New devices and strategies have been developed to prevent VAP. Some of these are promising but need further study. In addition, more attention is being given to factors that might facilitate the implementation process and the challenge of achieving high adherence rates.
引用
收藏
页码:155 / 159
页数:5
相关论文
共 35 条
[1]
Limiting the attributable mortality of nosocomial infection and multidrug resistance in intensive care units [J].
Blot, S. .
CLINICAL MICROBIOLOGY AND INFECTION, 2008, 14 (01) :5-13
[2]
Evidence-based guidelines for the prevention of ventilator-associated pneumonia: results of a knowledge test among intensive care nurses [J].
Blot, Stijn I. ;
Labeau, Sonia ;
Vandijck, Dominique ;
Van Aken, Paul ;
Claes, Brigitte .
INTENSIVE CARE MEDICINE, 2007, 33 (08) :1463-1467
[3]
Long-Term Impact of a Multifaceted Prevention Program on Ventilator-Associated Pneumonia in a Medical Intensive Care Unit [J].
Bouadma, Lila ;
Deslandes, Emmanuelle ;
Lolom, Isabelle ;
Le Corre, Bertrand ;
Mourvillier, Bruno ;
Regnier, Bernard ;
Porcher, Raphael ;
Wolff, Michel ;
Lucet, Jean-Christophe .
CLINICAL INFECTIOUS DISEASES, 2010, 51 (10) :1115-1122
[4]
Changes in knowledge, beliefs, and perceptions throughout a multifaceted behavioral program aimed at preventing ventilator-associated pneumonia [J].
Bouadma, Lila ;
Mourvillier, Bruno ;
Deiler, Veronique ;
Derennes, Nelly ;
Le Corre, Bertrand ;
Lolom, Isabelle ;
Regnier, Bernard ;
Wolff, Michel ;
Lucet, Jean-Christophe .
INTENSIVE CARE MEDICINE, 2010, 36 (08) :1341-1347
[5]
A multifaceted program to prevent ventilator-associated pneumonia: Impact on compliance with preventive measures [J].
Bouadma, Lila ;
Mourvillier, Bruno ;
Deiler, Veronique ;
Le Corre, Bertrand ;
Lolom, Isabelle ;
Regnier, Bernard ;
Wolff, Michel ;
Lucet, Jean-Christophe .
CRITICAL CARE MEDICINE, 2010, 38 (03) :789-796
[6]
Saline instillation before tracheal suctioning decreases the incidence of ventilator-associated pneumonia [J].
Caruso, Pedro ;
Denari, Silvia ;
Ruiz, Soraia A. L. ;
Demarzo, Sergio E. ;
Deheinzelin, Daniel .
CRITICAL CARE MEDICINE, 2009, 37 (01) :32-38
[7]
Oral hygiene with chlorhexidine on the prevention of ventilator-associated pneumonia in intubated patients: A systematic review of randomized clinical trials [J].
Carvajal, Carlos ;
Pobo, Angel ;
Diaz, Emili ;
Lisboa, Thiago ;
Llaurado, Mireia ;
Rello, Jordi .
MEDICINA CLINICA, 2010, 135 (11) :491-497
[8]
Effect of tracheal tube cuff shape on fluid leakage across the cuff: an in vitro study [J].
Dave, M. H. ;
Frotzler, A. ;
Spielmann, N. ;
Madjdpour, C. ;
Weiss, M. .
BRITISH JOURNAL OF ANAESTHESIA, 2010, 105 (04) :538-543
[9]
BEHAVIORAL DETERMINANTS OF HAND HYGIENE COMPLIANCE IN INTENSIVE CARE UNITS [J].
De Wandel, David ;
Maes, Lea ;
Labeau, Sonia ;
Vereecken, Carine ;
Blot, Stijn .
AMERICAN JOURNAL OF CRITICAL CARE, 2010, 19 (03) :230-238
[10]
CRITICAL CARE CLINICIANS' KNOWLEDGE OF EVIDENCE-BASED GUIDELINES FOR PREVENTING VENTILATOR-ASSOCIATED PNEUMONIA [J].
El-Khatib, Mohamad F. ;
Zeineldine, Salah ;
Ayoub, Chakib ;
Husari, Ahmad ;
Bou-Khalil, Pierre K. .
AMERICAN JOURNAL OF CRITICAL CARE, 2010, 19 (03) :272-276