Are children with Kawasaki disease and prolonged fever at risk for macrophage activation syndrome?

被引:43
作者
Muise, A
Tallett, SE
Silverman, ED
机构
[1] Univ Toronto, Hosp Sick Children, Div Rheumatol, Toronto, ON M5G 1X8, Canada
[2] Univ Toronto, Hosp Sick Children, Dept Paediat, Toronto, ON M5G 1X8, Canada
[3] Univ Toronto, Hosp Sick Children, Div Pediat Med, Toronto, ON M5G 1X8, Canada
[4] Univ Toronto, Hosp Sick Children, Dept Immunol, Toronto, ON M5G 1X8, Canada
关键词
Kawasaki disease; macrophage activation syndrome; hemophagocytosis; intravenous immunoglobulin;
D O I
10.1542/peds.112.6.e495
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Kawasaki disease ( KD) patients are known to be at increased risk for coronary artery lesions. We present evidence of another possible complication associated with KD: macrophage activation syndrome ( MAS). In this case, a patient with KD and prolonged fever developed MAS. This case is of particular interest because of the late age of onset and recurrent nature of KD as well as the complication of MAS. We also present a review of the literature that supports the inclusion of MAS as an infrequent complication of KD.
引用
收藏
页码:E495 / E497
页数:3
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