Y-chromosome haplotype distribution in Han Chinese populations and modern human origin in East Asians

被引：23

作者：

Ke, YH

Su, B

Xiao, JH

Chen, H

Huang, W

Chen, Z

Chu, JY

Tan, JZ

Jin, L

Lu, DR ^{[1
]}

机构：

[1] Fudan Univ, Inst Genet, Shanghai 200433, Peoples R China

[2] Fudan Univ, Morgan Tan Int Ctr Life Sci, Shanghai 200433, Peoples R China

[3] Chinese Acad Sci, Kunming Inst Zool, Kunming 650223, Peoples R China

[4] Univ Texas, Ctr Human Genet, Houston, TX 77225 USA

[5] Natl Human Genome Ctr, Shanghai 201203, Peoples R China

[6] Chinese Acad Med Sci, Med Biol Inst, Kunming, Peoples R China

来源：

SCIENCE IN CHINA SERIES C-LIFE SCIENCES | 2001年 / 44卷 / 03期

基金：

中国国家自然科学基金;

关键词：

Y-chromosome haplotype; SNPs; modern human origin; emigration; Chinese;

D O I：

10.1007/BF02879329

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We investigated the distribution of Y-chromosome haplotype using 19 Y-SNPs in Han Chinese populations from 22 provinces of China. Our data indicate distinctive patterns of Y chromosome between southern and northern Han Chinese populations. The southern populations are much more polymorphic than northern populations. The latter has only a subset of the southern haplotypes. This result confirms the genetic difference observed between southern and northern ethnic populations in East Asia. It supports the hypothesis that the first settlement of modern humans of African origin occurred in the southern part of East Asia during the last Ice Age, and a northward migration led to the peopling of northern China.

引用

页码：225 / 232

页数：8

共 29 条

[1]

BALLINGER SW, 1992, GENETICS, V130, P139

[2] Characterization of ancestral and derived Y-chromosome haplotypes of new world native populations [J].