On distance and similarity in fold space

被引：52

作者：

Sippl, Manfred J. ^{[1
]}

机构：

[1] Salzburg Univ, Ctr Appl Mol Engn, Div Bioinformat, Dept Mol Biol, A-5020 Salzburg, Austria

来源：

BIOINFORMATICS | 2008年 / 24卷 / 06期

关键词：

D O I：

10.1093/bioinformatics/btn040

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Metric information on similarities and distances in fold space is essential for quantitative work in structural bioinformatics and structural biology. Here we derive a suitable metric for protein structures from the fundamental axioms of similarity. Derivation of the metric also clarifies the relationship between the interrelated concepts of distance and similarity.

引用

页码：872 / 873

页数：2

共 8 条

[1]

Feng ZK, 1996, FOLD DES, V1, P123

[2]

Lackner P, 1999, PROTEINS, P7

[3] A discrete view on fold space [J].

Sippl, Manfred J. ;

Suhrer, Stefan J. ;

Gruber, Markus ;

Wiederstein, Markus .

BIOINFORMATICS, 2008, 24 (06) :870-871

[4] A note on difficult structure alignment problems [J].

Sippl, Manfred J. ;

Wiederstein, Markus .

BIOINFORMATICS, 2008, 24 (03) :426-427

[5]

Sippl MJ, 2001, PROTEINS, P55

[6] ON THE PROBLEM OF COMPARING PROTEIN STRUCTURES - DEVELOPMENT AND APPLICATIONS OF A NEW METHOD FOR THE ASSESSMENT OF STRUCTURAL SIMILARITIES OF POLYPEPTIDE CONFORMATIONS [J].

SIPPL, MJ .

JOURNAL OF MOLECULAR BIOLOGY, 1982, 156 (02) :359-388

[7] QSCOP-SCOP quantified by structural relationships [J].

Suhrer, Stefan J. ;

Wiederstein, Markus ;

Sippl, Manfred J. .

BIOINFORMATICS, 2007, 23 (04) :513-514

[8] Evolutionary transitions in protein fold space [J].

Taylor, William R. .

CURRENT OPINION IN STRUCTURAL BIOLOGY, 2007, 17 (03) :354-361

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