Phenolics from Maytenus senegalensis

被引：41

作者：

Hussein, G ^{[1
]}

Nakamura, N ^{[1
]}

Meselhy, MR ^{[1
]}

Hattori, M ^{[1
]}

机构：

[1] Toyama Med & Pharmaceut Univ, Res Inst Tradit Sino Japanese Med, Toyama 9300194, Japan

来源：

PHYTOCHEMISTRY | 1999年 / 50卷 / 04期

关键词：

Maytenus senegalensis; Celastraceae; methylated flavan-3-ols; proanthocyanidins;

D O I：

10.1016/S0031-9422(98)00571-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two new methylated flavan-3-ol glucosides and a methylated proanthocyanidin were isolated from the MeOH extract of the stem-bark of Maytenus senegalensis, together with five known compounds. The structures of the new compounds were determined as: (-)-4'-methylepigallocatechin 5-O-beta-glucopyranoside, (+)-4'-methylgallocatechin 3'-O-beta-glucopyranoside and (-)-epicatechin (4 beta --> 8) (-)-4'-methylepigallocatechin by chemical and spectroscopic means. The MeOH and H2O extracts showed moderate inhibitory effects against HIV-1 protease. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：689 / 694

页数：6

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