Molecular chaperones: Small heat shock proteins in the limelight

被引：67

作者：

van den IJssel, P ^{[1
]}

Norman, DG ^{[1
]}

Quinlan, RA ^{[1
]}

机构：

[1] Univ Dundee, Dept Biochem, Dundee DD1 5EH, Scotland

来源：

CURRENT BIOLOGY | 1999年 / 9卷 / 03期

关键词：

D O I：

10.1016/S0960-9822(99)80061-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Small heat shock proteins have been the Cinderellas of the molecular chaperone world, but now the crystal structure of a small heat shock protein has been solved and mutation of two human homologues implicated in genetic disease. Intermediate filaments appear to be one of the key targets of their chaperone activity.

引用

页码：R103 / R105

页数：3

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