Substituted 1,6-naphthyridines as human cytomegalovirus inhibitors:: Conformational requirements

被引：14

作者：

Falardeau, G ^{[1
]}

Chan, L ^{[1
]}

Stefanac, T ^{[1
]}

May, S ^{[1
]}

Jin, HL ^{[1
]}

Lavallée, JF ^{[1
]}

机构：

[1] BioChem Pharma Inc, Laval, PQ H7V 4A7, Canada

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2000年 / 10卷 / 24期

关键词：

D O I：

10.1016/S0960-894X(00)00568-0

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Substituted 1,6-naphthyridine derivatives, a new class of human cytomegalovirus inhibitors, were prepared to demonstrate the role of intramolecular hydrogen bonds to maintain the compounds in their active conformation. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：2769 / 2770

页数：2

共 4 条

[1]

*AM1, HYP PRO 5 1

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