Enantioselective conjugate addition of diethylzinc to cyclohexenone catalyzed by a chiral aminophosphine-copper(II) triflate

被引：55

作者：

Mori, T ^{[1
]}

Kosaka, K ^{[1
]}

Nakagawa, Y ^{[1
]}

Nagaoka, Y ^{[1
]}

Tomioka, K ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Pharmaceut Sci, Sakyo Ku, Kyoto 6068501, Japan

来源：

TETRAHEDRON-ASYMMETRY | 1998年 / 9卷 / 18期

基金：

日本学术振兴会;

关键词：

D O I：

10.1016/S0957-4166(98)00348-6

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Enantioselective conjugate addition of diethylzinc to cyclohexenone and 4,4-dimethylcyclohexenone was catalyzed by the combination of 0.1 equiv. of a chiral monodentate aminophosphine 3 and 0.05 equiv. of copper(If) triflate to give the corresponding adducts 4 in up to 70% ee. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：3175 / 3178

页数：4