High prevalence of glycopeptide resistance genes vanB, vanD, and vanG not associated with enterococci in human fecal flora

被引：53

作者：

Domingo, MC

Huletsky, A

Giroux, R

Boissinot, K

Picard, FJ

Lebel, P

Ferraro, MJ

Bergeron, MG

机构：

[1] Univ Laval, CHUQ, Ctr Rech Infectiol, Quebec City, PQ G1V 4G2, Canada

[2] Univ Laval, Fac Med, Div Microbiol, Laval, PQ, Canada

[3] McGill Univ, Ctr Hlth, Hop Gen Montreal, Dept Microbiol, Montreal, PQ, Canada

[4] Harvard Univ, Sch Med, Massachusetts Gen Hosp, Dept Clin Microbiol, Boston, MA USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2005年 / 49卷 / 11期

关键词：

D O I：

10.1128/AAC.49.11.4784-4786.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The presence of Enterococcus-associated vancomycin resistance genes vanA, vanB, vanD, vanE, and vanG in rectal swabs was investigated in two hospitals using PCR. All vanA genes detected were associated with vancomycin-resistant enterococci (VRE), whereas VRE-associated vanB genes were detected in only one hospital (4.7%). However, in both hospitals, high prevalences of vanB (6.2 and 2.3%), vanD (43.8 and 26.7%), and vanG (10.5 and 6.9%) genes not associated with enterococci were found.

引用

页码：4784 / 4786

页数：3

共 7 条

[1] Molecular characterization of vanB elements in naturally occurring gut anaerobes
Ballard, SA
Pertile, KK
Lim, M
Johnson, PDR
Grayson, ML
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (05) : 1688 - 1694
[2] Comparison of three PCR primer sets for identification of vanB gene carriage in feces and correlation with carriage of vancomycin-resistant enterococci:: Interference by vanB-containing anaerobic bacilli
Ballard, SA
Grabsch, EA
Johnson, PDR
Grayson, ML
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (01) : 77 - 81
[3] Characterization of a Tn5382-like transposon containing the vanB2 gene cluster in a Clostridium strain isolated from human faeces
Domingo, MC
Huletsky, A
Bernal, A
Giroux, R
Boudreau, DK
Picard, FJ
Bergeron, MG
[J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2005, 55 (04) : 466 - 474
[4] Ke DB, 2000, CLIN CHEM, V46, P324
[5] Clinical impact of vancomycin-resistant enterococci
Patel, R
[J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2003, 51 : 13 - 21
[6] Enterococcal vanB resistance locus in anaerobic bacteria in human faeces
Stinear, TP
Olden, DC
Johnson, PDR
Davies, JK
Grayson, ML
[J]. LANCET, 2001, 357 (9259) : 855 - 856
[7] Epidemiology of the genetic elements responsible for acquired glycopeptide resistance in enterococci
Woodford, N
[J]. MICROBIAL DRUG RESISTANCE, 2001, 7 (03) : 229 - 236

← 1 →