Regeneration and gene regulation in planarians

被引:72
作者
Agata, K [1 ]
机构
[1] RIKEN Kobe, Ctr Dev Biol, Evolutionary Regenerat Grp, Chuo Ku, Kobe, Hyogo 6500047, Japan
关键词
D O I
10.1016/j.gde.2003.08.009
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Planarians can regenerate using a pluripotent stem cell system. This phenomenon provides a unique opportunity to understand gene regulation in the process of differentiation from pluripotent stem cells. Recent studies have made significant advances in our understanding of the pluripotent stem cell system in this model. In particular, a gene knockdown method by RNA interference enabled great progress in identifying genes involved in regeneration and stem cell regulation.
引用
收藏
页码:492 / 496
页数:5
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