A double blind, placebo-controlled study to assess the effect of famciclovir on virus replication in patients with chronic hepatitis B virus infection

被引：104

作者：

Main, J ^{[1
]}

Brown, JL ^{[1
]}

Howells, C ^{[1
]}

Galassini, R ^{[1
]}

Crossey, M ^{[1
]}

Karayiannis, P ^{[1
]}

Georgiou, P ^{[1
]}

Atkinson, G ^{[1
]}

Thomas, HC ^{[1
]}

机构：

[1] SMITHKLINE BEECHAM PHARMACEUT,HARLOW CM19 5AD,ESSEX,ENGLAND

来源：

JOURNAL OF VIRAL HEPATITIS | 1996年 / 3卷 / 04期

关键词：

famciclovir; hepatitis B virus; nucleoside analogue;

D O I：

10.1111/j.1365-2893.1996.tb00098.x

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

This is the first double-blind controlled study of famciclovir, an oral antiviral agent, as potential therapy for chronic hepatitis B virus (HBV) carriers. A fall of more than 90% in HBV DNA levels was noted in six of 11 evaluable patients treated with a 10 day course of oral famciclovir. Further studies with more prolonged therapy are ongoing.

引用

页码：211 / 215

页数：5

共 21 条

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