Mapping human epilepsy genes - Implications for the treatment of epilepsy

被引：4

作者：

Serratosa, JM

DelgadoEscueta, AV

机构：

[1] W LOS ANGELES DVA MED CTR,COMPREHENS EPILEPSY PROGRAM 127B,NEUROL SERV,LOS ANGELES,CA 90073

[2] W LOS ANGELES DVA MED CTR,COMPREHENS EPILEPSY PROGRAM 127B,RES SERV,LOS ANGELES,CA 90073

来源：

CNS DRUGS | 1996年 / 5卷 / 03期

关键词：

FAMILIAL NEONATAL CONVULSIONS; MYOCLONIC EPILEPSY; ASSIGNMENT; DISEASE;

D O I：

10.2165/00023210-199605030-00001

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Recent and ongoing advances in mapping and isolating human epilepsy genes will: (i) modify the classification of the epilepsies; (ii) base antiepileptic drug development on defined epilepsy mutations; and (iii) spur the development of somatic cell and/or germ line therapy for the fatal progressive myoclonus epilepsies and, eventually, the chronic generalised and partial epilepsies. In the next century, advances in these 3 areas will dramatically change the diagnostic, therapeutic and prognostic approach to patients with epilepsy, and will probably eliminate some genetic epilepsies within 2 or 3 generations.

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收藏

页码：155 / 159

页数：5

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