The medical treatment of inflammatory breast cancer

被引:35
作者
Dawood, Shaheenah [2 ]
Ueno, Naoto T. [1 ,3 ]
Cristofanilli, Massimo [1 ]
机构
[1] Univ Texas Houston, MD Anderson Canc Ctr, Breast Med Oncol Dept,Unit 1354, Morgan Welch Inflammatory Breast Canc Res & Clin, Houston, TX 77030 USA
[2] Dubai Hosp, Dept Med Oncol, Dubai, U Arab Emirates
[3] Univ Texas Houston, MD Anderson Canc Ctr, Breast Canc Res Lab, Dept Stem Cell Translat & Cellular Therapy, Houston, TX 77030 USA
关键词
D O I
10.1053/j.seminoncol.2007.11.012
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
The multidisciplinary management of inflammatory breast cancer (IBC) includes neoadjuvant systemic chemotherapy, surgery, radiotherapy, and, in hormone receptor-positive disease, hormonal therapy. The use of induction chemotherapy with anthracyclines and taxanes somewhat improved the prognosis and local control of patients with IBC compared to local modalities alone. Improved understanding of the biological features of the disease has allowed for the development of targeted therapies (eg, trastuzumab and lapatinib) that are changing the outcome of this aggressive disease.
引用
收藏
页码:64 / 71
页数:8
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