Quantification of triiodinated benzene derivatives and X-ray contrast media in water samples by liquid chromatography-electrospray tandem mass spectrometry

被引：80

作者：

Putschew, A ^{[1
]}

Schittko, S ^{[1
]}

Jekel, M ^{[1
]}

机构：

[1] Tech Univ Berlin, Inst Environm Technol, Dept Water Qual Control, D-10623 Berlin, Germany

来源：

JOURNAL OF CHROMATOGRAPHY A | 2001年 / 930卷 / 1-2期

关键词：

water analysis; liquid chromatography-tandem mass spectrometry; X-ray contrast media; triiodinated benzene derivatives;

D O I：

10.1016/S0021-9673(01)01186-4

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A method for the analysis of iodinated X-ray contrast media and possible metabolites in environmental water samples is presented. The method consists of a sequential solid-phase extraction followed by high-performance liquid chromatography coupled with tandem mass spectrometry for detection. The recoveries for the analytes in tap water varies between 70 and 100%. For matrix poor samples the detection limit is in the lower ng/l range. In case of native, complex samples the recoveries are lower and the parallel analysis of a spiked sample is necessary to obtain reliable data. With the presented method iodinated X-ray contrast media could be detected and quantified in a sewage treatment plant effluent, in a receiving channel and lake. In the receiving lake the concentrations are still high with values between 0.5 and 4 mug/l. (C) 2001 Elsevier Science B.V All rights reserved.

引用

页码：127 / 134

页数：8

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