A convenient preparation of 4-iodoindoles from indoles: application to the chemical synthesis of hapalindole alkaloids

被引：39

作者：

Brown, MA ^{[1
]}

Kerr, MA ^{[1
]}

机构：

[1] Univ Western Ontario, Dept Chem, London, ON N6A 5B9, Canada

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 06期

基金：

加拿大自然科学与工程研究理事会;

关键词：

D O I：

10.1016/S0040-4039(00)02194-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

4-Iodoindoles were synthesized via regioselective chloromercuration and subsequent iodination of a series of N-p-toluenesulfonyl indoles bearing a variety of substituents at the 3-position This procedure allows rapid access to 3,4-dihaloindoles which may be used as synthetic precursors to indole alkaloids. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：983 / 985

页数：3

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