Spatio-temporal epidemiology of Campylobacter jejuni enteritis, in an area of Northwest England, 2000-2002

被引:16
作者
Gabriel, E. [1 ,2 ]
Wilson, D. J. [2 ,3 ]
Leatherbarrow, A. J. H. [4 ]
Cheesbrough, J. [4 ]
Gee, S. [4 ]
Bolton, E. [5 ]
Fox, A. [5 ]
Fearnhead, P. [2 ]
Hart, C. A. [4 ]
Diggle, P. J. [2 ]
机构
[1] Univ Avignon, IUT STID, F-84911 Avignon 9, France
[2] Univ Lancaster, Lancaster, England
[3] Univ Chicago, Chicago, IL 60637 USA
[4] Univ Liverpool, Liverpool L69 3BX, Merseyside, England
[5] Royal Preston Hosp, Preston, Lancs, England
关键词
Campylobacter; infectious disease epidemiology; statistics; zoonotic foodborne diseases; 2ND-ORDER ANALYSIS; POINT PROCESS;
D O I
10.1017/S0950268810000488
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
A total of 969 isolates of Campylobacter jejuni originating in the Preston, Lancashire postcode district over a 3-year period were characterized using multi-locus sequence typing. Recently developed statistical methods and a genetic model were used to investigate temporal, spatial, spatio-temporal and genetic variation in human C. jejuni infections. The analysis of the data showed statistically significant seasonal variation, spatial clustering, small-scale spatio-temporal clustering and spatio-temporal interaction in the overall pattern of incidence, and spatial segregation in cases classified according to their most likely species-of-origin.
引用
收藏
页码:1384 / 1390
页数:7
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