Thermal modelling of Ohmic heating microreactors

被引:12
作者
Cordero, N [1 ]
West, J [1 ]
Berney, H [1 ]
机构
[1] Natl Univ Ireland Univ Coll Cork, NMRC, Cork, Ireland
关键词
microreactor; micromachining; Ohmic heating; Joule effect heating; thermal modelling; thermal simulation; transient thermal modelling;
D O I
10.1016/S0026-2692(03)00204-0
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
This paper describes the static and transient thermal modelling of an Ohmic heating microreactor for biological sample processing for the purpose of genetic analysis. Precise thermal management can be used for the effective preparation of analyte DNA molecules prior to detection. Due to the small dimensions of the microreactor, the direct measurement and monitoring of the temperature distribution presents a challenge. To overcome this, thermal modelling has been used to accurately predict the thermal behaviour of the microreactor and sample component. It is further possible to calculate the required input power levels and provide design criteria to optimise the design of the microreactor. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1137 / 1142
页数:6
相关论文
共 13 条
[1]   Fundamental principles of electrochemical ohmic heating of solutions [J].
Amatore, C ;
Berthou, M ;
Hebert, S .
JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 1998, 457 (1-2) :191-203
[2]   Thermal behaviour of a solid/liquid mixture in an ohmic heating sterilizer - slip phase model [J].
Benabderrahmane, Y ;
Pain, JP .
CHEMICAL ENGINEERING SCIENCE, 2000, 55 (08) :1371-1384
[3]  
CORDERO N, 2003, P EUROSIME, P85
[4]   METHODS FOR INVESTIGATION OF IONIC REACTIONS IN AQUEOUS SOLUTIONS WITH HALF-TIMES AS SHORT AS 10-9 SEC - APPLICATION TO NEUTRALIZATION AND HYDROLYSIS REACTIONS [J].
EIGEN, M .
DISCUSSIONS OF THE FARADAY SOCIETY, 1954, (17) :194-205
[5]  
*FLOM INC, 2001, FLOTHERM V3 2 US MAN
[6]   Simulation and verification of two-dimensional ohmic heating in static system [J].
Fu, WR ;
Hsieh, CC .
JOURNAL OF FOOD SCIENCE, 1999, 64 (06) :946-949
[7]  
GOODWIN DC, 1993, BIOTECHNIQUES, V15, P438
[8]  
HEAP DM, 2000, BIOTECHNIQUES EURO E, V29, P46
[9]   MINIATURIZED TOTAL CHEMICAL-ANALYSIS SYSTEMS - A NOVEL CONCEPT FOR CHEMICAL SENSING [J].
MANZ, A ;
GRABER, N ;
WIDMER, HM .
SENSORS AND ACTUATORS B-CHEMICAL, 1990, 1 (1-6) :244-248
[10]   Ohmic heating of solid-liquid mixtures: A comparison of mathematical models under worst-case heating conditions [J].
Sastry, SK ;
Salengke, S .
JOURNAL OF FOOD PROCESS ENGINEERING, 1998, 21 (06) :441-458