Association study of polymorphisms within matrix metalloproteinase 9 with bronchial asthma

被引:23
作者
Ganter, K [1 ]
Deichmann, KA [1 ]
Heinzmann, A [1 ]
机构
[1] Univ Freiburg, Univ Childrens Hosp, D-79106 Freiburg, Germany
关键词
D O I
10.1111/j.1744-313X.2005.00516.x
中图分类号
Q3 [遗传学];
学科分类号
071007 [遗传学]; 090102 [作物遗传育种];
摘要
Matrix metalloproteinase 9 plays an important role in the development of bronchial asthma. We were interested in whether the polymorphisms -T1702A, -C1562T, R279Q and +C6T within the matrix metalloproteinase 9 (MMP-9) gene were associated with asthma in a population of 231 asthmatic children. However, we found no association. Thus MMP-9 might not be a major gene for asthma.
引用
收藏
页码:233 / 236
页数:4
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