A tale of too many centrosomes

被引：31

作者：

Acilan, Ceyda ^{[2
]}

Saunders, William S. ^{[1
]}

机构：

[1] Univ Pittsburgh, Dept Biol Sci, Pittsburgh, PA 15235 USA

[2] Istanbul Tech Univ, BioT Incorp, TR-34390 Istanbul, Turkey

来源：

CELL | 2008年 / 134卷 / 04期

关键词：

D O I：

10.1016/j.cell.2008.08.007

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Having the correct number of centrosomes is crucial for proper chromosome segregation during cell division and for the prevention of aneuploidy, a hallmark of many cancer cells. Several recent studies (Basto et al., 2008; Kwon et al., 2008; Yang et al., 2008) reveal the importance of mechanisms that protect against the consequences of harboring too many centrosomes.

引用

页码：572 / 575

页数：4

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