Familial hypercholesterolemia: Current treatment options and patient selection for low-density lipoprotein apheresis

被引：19

作者：

Hemphill, Linda C. ^{[1
]}

机构：

[1] Massachusetts Gen Hosp, Dept Cardiol, Yawkey Ctr, Boston, MA 02114 USA

来源：

JOURNAL OF CLINICAL LIPIDOLOGY | 2010年 / 4卷 / 05期

关键词：

Familial hypercholesterolemia; LDL; Apheresis; Statins; Patient selection; CORONARY-HEART-DISEASE; EFFICACY; ATORVASTATIN; SAFETY; ROSUVASTATIN; SIMVASTATIN; CHILDREN; THERAPY; EZETIMIBE; PROGRAM;

D O I：

10.1016/j.jacl.2010.08.013

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Options for treatment of severe heterozygous and homozygous familial hypercholesterolemia prior to the statin era were limited by significant side effects and morbidity. The advent of both the statins and technology for the selective removal of LDL via apheresis have revolutionized management but challenges remain. (C) 2010 National Lipid Association. All rights reserved.

引用

页码：346 / 349

页数：4

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