Counts of neutrophils, lymphocytes, and monocytes, cause-specific mortality and coronary heart disease: The NHANES-1 epidemiologic follow-up study

被引：103

作者：

Gillum, RF ^{[1
]}

Mussolino, ME ^{[1
]}

Madans, JH ^{[1
]}

机构：

[1] Natl Ctr Hlth Stat, Off Anal & Epidemiol, Ctr Dis Control & Prevent, Hyattsville, MD 20782 USA

来源：

ANNALS OF EPIDEMIOLOGY | 2005年 / 15卷 / 04期

关键词：

leukocyte count; neutrophils; coronary disease; mortality;

D O I：

10.1016/j.annepidem.2004.08.009

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

PURPOSE: To examine the association of elevated counts of white blood cell types with increased risk of coronary heart disease (CHD) and death. METHODS: Data were examined from the NHANES-I Epidemiologic Follow-up Study. RESULTS: Relative risks for death at ages 25 to 74 comparing the upper and lower tertiles of neutrophil count were: all causes 1.29 (95% CL, 1.14, 1.47), and cardiovascular causes 1.39 (95% CL, 1.15, 1.67) after adjusting for baseline risk factors. CONCLUSIONS: The increased risk of CHD and death from all causes and cardiovascular diseases appeared to be only partially due to effects of smoking. No association was seen for lymphocytes or monocytes. (c) 2004 Elsevier Inc. All rights reserved.

引用

页码：266 / 271

页数：6

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