'Upenamide:: An unprecedented macrocyclic alkaloid from the Indonesian sponge Echinochalina sp.

被引：32

作者：

Jiménez, JI

Goetz, G

Mau, CMS

Yoshida, WY

Scheuer, PJ ^{[1
]}

Williamson, RT

Kelly, M

机构：

[1] Univ Hawaii Manoa, Dept Chem, Honolulu, HI 96822 USA

[2] Oregon State Univ, Coll Pharm, Corvallis, OR 97331 USA

[3] NIWA, Marine Ecol & Aquaculture Grp, Auckland, New Zealand

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2000年 / 65卷 / 25期

关键词：

D O I：

10.1021/jo000789w

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

'Upenamide (1) represents a new class of macrocyclic marine alkaloid possessing both spiro-oxaquinolizidinone and hemiaminal ring systems. It was isolated from the Indonesian sponge Echinochalina sp. The gross structure of I was:elucidated by spectroscopic methods and accurate mass measurements. A suggestion is made as to its biogenetic origin.

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页码：8465 / 8469

页数：5

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