Fetal valproate syndrome and autism: additional evidence of an association

被引：292

作者：

Williams, G

King, J

Cunningham, M

Stephan, M

Kerr, B

Hersh, JH

机构：

[1] Univ Louisville, Childrens Evaluat Ctr, Louisville, KY 40202 USA

[2] USN, Med Ctr, Dept Pediat, San Diego, CA USA

[3] Univ Washington, Div Genet & Dev, Childrens Craniofacial Ctr, Seattle, WA 98195 USA

[4] Madigan Army Med Ctr, Dept Pediat, Tacoma, WA 98431 USA

[5] Royal Manchester Childrens Hosp, Dept Genet, Manchester M27 1HA, Lancs, England

来源：

DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY | 2001年 / 43卷 / 03期

关键词：

D O I：

10.1017/S001216220100038X

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Autism has been described in association with a variety of medical and genetic conditions. We previously reported on a patient whose clinical phenotype was compatible with both fetal valproate syndrome (FVS) and autism. Here we present five additional patients with FVS and autism. In all five of our patients, there was evidence of cognitive deficits, manifestations of autism, and typical phenotypic characteristics of FVS. The association between this known teratogen and autism has both clinical and research implications.

引用

页码：202 / 206

页数：5

共 31 条

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