Is ASDAS better than BASDAI as a measure of disease activity in axial psoriatic arthritis?

被引:76
作者
Eder, Lihi
Chandran, Vinod
Shen, Hua [2 ]
Cook, Richard J. [2 ]
Gladman, Dafna D. [1 ]
机构
[1] Univ Toronto, Toronto Western Hosp, Psoriat Arthrit Clin, Ctr Prognosis Studies Rheumat Dis, Toronto, ON M5T 2S8, Canada
[2] Univ Waterloo, Dept Stat & Actuarial Sci, Waterloo, ON N2L 3G1, Canada
基金
加拿大健康研究院;
关键词
ANKYLOSING-SPONDYLITIS; ACTIVITY INDEX; CLASSIFICATION; CRITERIA; SCORE;
D O I
10.1136/ard.2010.129726
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Objective To assess the discriminative ability and correlation of the Ankylosing Spondylitis Disease Activity Score (ASDAS) and Bath Ankylosing Spondylitis Activity Disease Activity Index (BASDAI) with disease activity in axial psoriatic arthritis (AxPsA). Methods Patients with AxPsA were selected from a large prospective cohort study of psoriatic arthritis. Patient and physician global scores were used as constructs of disease activity. Patients were categorised into high and low disease activity states based on patient and physician global assessment scores and physician's decision to change treatment. Statistical analysis included descriptive statistics, linear and logistic regression. Results 201 patients with AxPsA were included in the study. ASDAS and BASDAI showed good correlation with disease activity as reflected by the patient global score (correlation coefficients (r) for BASDAI 0.84, ASDAS-B 0.77, ASDAS-C 0.81, p<0.001) and the physician global score (r=0.53 for BASDAI, r=0.50 for ASDAS-B, r=0.55 for ASDAS-C, p<0.001). Both scores showed good discriminative ability between high and low disease activity states. However, there were no significant differences between areas under the curve for the models that compared ASDAS with BASDAI for each definition of disease activity state. Conclusions In patients with AxPsA, ASDAS and BASDAI scores show similar good to moderate discriminative ability and correlation with different constructs of disease activity. ASDAS was not superior to BASDAI in its ability to discriminate between high and low disease activity states in AxPsA.
引用
收藏
页码:2160 / 2164
页数:5
相关论文
共 14 条
[1]
Risk Factors for Axial Inflammatory Arthritis in Patients with Psoriatic Arthritis [J].
Chandran, Vinod ;
Tolusso, David C. ;
Cook, Richard J. ;
Gladman, Dafna D. .
JOURNAL OF RHEUMATOLOGY, 2010, 37 (04) :809-815
[2]
Axial Psoriatic Arthritis: Update on a Longterm Prospective Study [J].
Chandran, Vinod ;
Barrett, Jessica ;
Schentag, Catherine T. ;
Farewell, Vernon T. ;
Gladman, Dafna D. .
JOURNAL OF RHEUMATOLOGY, 2009, 36 (12) :2744-2750
[3]
GARRETT S, 1994, J RHEUMATOL, V21, P2286
[4]
KENNEDY LG, 1995, BRIT J RHEUMATOL, V34, P767
[5]
Evaluation of Ankylosing Spondylitis Spinal Mobility Measurements in the Assessment of Spinal Involvement in Psoriatic Arthritis [J].
Luis Fernandez-Sueiro, Jose ;
Willisch, Alfredo ;
Pertega-Diaz, Sonia ;
Pinto Tasende, Jose Antonio ;
Fernandez-Lopez, Carlos ;
Galdo, Fausto ;
Javier Blanco, Francisco .
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH, 2009, 61 (03) :386-392
[6]
Development of an ASAS-endorsed disease activity score (ASDAS) in patients with ankylosing spondylitis [J].
Lukas, C. ;
Landewe, R. ;
Sieper, J. ;
Dougados, M. ;
Davis, J. ;
Braun, J. ;
van der Linden, S. ;
van der Heijde, D. .
ANNALS OF THE RHEUMATIC DISEASES, 2009, 68 (01) :18-24
[7]
Psoriatic arthritis assessment tools in clinical trials [J].
Mease, PJ ;
Antoni, CE ;
Gladman, DD ;
Taylor, WJ .
ANNALS OF THE RHEUMATIC DISEASES, 2005, 64 :49-54
[8]
O'Shea FD, 2006, ARTHRITIS RHEUM, V54, P4091
[9]
Responsiveness of the Ankylosing Spondylitis Disease Activity Score (ASDAS) and clinical and MRI measures of disease activity in a 1-year follow-up study of patients with axial spondyloarthritis treated with tumour necrosis factor α inhibitors [J].
Pedersen, Susanne Juhl ;
Sorensen, Inge Juul ;
Hermann, Kay-Geert A. ;
Madsen, Ole Rintek ;
Tvede, Niels ;
Hansen, Michael Sejer ;
Thamsborg, Gorm ;
Andersen, Lis Smedegaard ;
Majgaard, Ole ;
Loft, Anne Gitte ;
Erlendsson, Jon ;
Asmussen, Karsten ;
Johansen, Julia S. ;
Jurik, Anne Grethe ;
Moller, Jakob ;
Hasselquist, Maria ;
Mikkelsen, Dorrit ;
Skjodt, Thomas ;
Hansen, Annette ;
Ostergaard, Mikkel .
ANNALS OF THE RHEUMATIC DISEASES, 2010, 69 (06) :1065-1071
[10]
An interpretation for the ROC curve and inference using GLM procedures [J].
Pepe, MS .
BIOMETRICS, 2000, 56 (02) :352-359