Mutations in K-ras codon 12 detected in plasma DNA are not an indicator of disease in patients with non-small cell lung cancer

被引：18

作者：

Trombino, S

Neri, M

Puntoni, R

Angelini, C

Loprevite, M

Cesario, A

Granone, P

Imperatori, A

Dominioni, L

Ardizzoni, A

Filiberti, R

Russo, P

机构：

[1] Natl Canc Inst, Dept Integrated Med Oncol DOMI, Unit Translat Res B Lung Canc, I-146132 Genoa, Italy

[2] Natl Canc Inst, Dept Integrated Med Oncol DOMI, Unit Epidemiol & Biostat, I-146132 Genoa, Italy

[3] Natl Canc Inst, Dept Integrated Med Oncol DOMI, Unit Med Oncol A, I-146132 Genoa, Italy

[4] Natl Canc Inst, Dept Integrated Med Oncol DOMI, Unit Mol Epidemiol, I-146132 Genoa, Italy

[5] Univ Genoa, Dept Biol, I-16126 Genoa, Italy

[6] Univ Cattolica Sacro Cuore, Gen Thorac Surg, I-00168 Rome, Italy

[7] Insubria Univ, Unit Thorac Surg, Varese, Italy

[8] Hosp Parma, Unit Med Oncol, Parma, Italy

[9] IRCCS, Translat & Clin Resp Pathol Lab, Rome, Italy

来源：

CLINICAL CHEMISTRY | 2005年 / 51卷 / 07期

关键词：

D O I：

10.1373/clinchem.2004.043976

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

引用

页码：1313 / 1314

页数：2

共 13 条

[1]

Ballaz Santiago, 2003, Clin Lung Cancer, V5, P46, DOI 10.3816/CLC.2003.n.021

[2] K-ras mutations in sera of patients with colorectal neoplasias and long-standing inflammatory bowel disease [J].

Borchers, R ;

Heinzlmann, M ;

Zahn, R ;

Witter, K ;

Martin, K ;

Loeschke, K ;

Folwaczny, C .

SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 2002, 37 (06) :715-718

[3] Comment on "Methylation patterns and K-ras mutations in tumor and paired serum of resected non-small-call lung cancer patients" (Cancer Letters 2003;193:207-216) [J].

Gautschi, O ;

Ziegler, A .

CANCER LETTERS, 2004, 204 (01) :1-1

[4] Screening for p53 and K-ras mutations in whole-gut lavage in chronic inflammatory bowel disease [J].

Heinzlmann, M ;

Lang, SM ;

Neynaber, S ;

Reinshagen, M ;

Emmrich, J ;

Stratakis, DF ;

Heldwein, W ;

Wiebecke, B ;

Loeschke, K .

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 2002, 14 (10) :1061-1066

[5] K-ras mutation in Helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer [J].

Hiyama, T ;

Haruma, K ;

Kitadai, Y ;

Masuda, H ;

Miyamoto, M ;

Tanaka, S ;

Yoshihara, M ;

Shimamoto, F ;

Chayama, K .

INTERNATIONAL JOURNAL OF CANCER, 2002, 97 (05) :562-566

[6] Stimulated human leukocytes cause activating mutations in the K-ras protooncogene [J].

Jackson, JH ;

Vollenweider, M ;

Hill, J ;

Rodriguez, H ;

Schwabacher, AW ;

Mitra, G ;

Kuo, CY .

ONCOGENE, 1997, 14 (23) :2803-2808

[7] Topographic analysis of K-ras mutations in histologically normal lung tissues and tumours of lung cancer patients [J].

Keohavong, P ;

Mady, HH ;

Gao, WM ;

Siegfried, JM ;

Luketich, JD ;

Melhem, MF .

BRITISH JOURNAL OF CANCER, 2001, 85 (02) :235-241

[8] Inhaled particles and lung cancer. Part A: Mechanisms [J].

Knaapen, AM ;

Borm, PJA ;

Albrecht, C ;

Schins, RPF .

INTERNATIONAL JOURNAL OF CANCER, 2004, 109 (06) :799-809

[9] Somatic mutation screening: Identification of individuals harboring K-ras mutations with the use of plasma DNA [J].

Kopreski, MS ;

Benko, FA ;

Borys, DJ ;

Khan, A ;

McGarrity, TJ ;

Gocke, CD .

JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2000, 92 (11) :918-923

[10] K-ras gene point mutation in neogenetic lesions of subpleural fibrotic lesions: Either an early genetic event in lung cancer development or a non-specific genetic change during the inflammatory reparative process [J].

Maeshima, AM ;

Maeshima, A ;

Kawashima, O ;

Nakajima, T .

PATHOLOGY INTERNATIONAL, 1999, 49 (05) :411-418

← 1 2 →