Should ambulatory blood pressure monitoring be mandatory for future studies in resistant hypertension: a perspective

被引:54
作者
Doumas, Michael [1 ]
Anyfanti, Panagiota [2 ]
Bakris, George [3 ]
机构
[1] George Washington Univ, Vet Affairs Med Ctr, Hypertens Unit, Washington, DC 20422 USA
[2] Aristotle Univ Thessaloniki, Prop Dept Internal Med 2, Hypertens Unit, GR-54006 Thessaloniki, Greece
[3] Univ Chicago, Pritzker Sch Med, Hypertens Dis Unit, Chicago, IL 60637 USA
关键词
ambulatory blood pressure; carotid baroreceptor activation; endothelin antagonists; interventional management; office blood pressure; renal sympathetic denervation; resistant hypertension; BAROREFLEX ACTIVATION THERAPY; RENAL SYMPATHETIC DENERVATION; WHITE-COAT; PREVALENCE;
D O I
10.1097/HJH.0b013e328352c3c7
中图分类号
R6 [外科学];
学科分类号
100210 [外科学];
摘要
Recent technologic advances rekindled interventional management of resistant hypertension, either by carotid baroreceptor activation or renal sympathetic denervation. Interventional techniques result in impressive falls in office blood pressure (BP); however, ambulatory BP reductions are rather modest. This disparity between office and ambulatory BP reductions is observed with antihypertensive drugs, but at a much lower degree. Available explanations are not convincing, therefore, we propose that sympathetic overactivity may partially explain this divergence. Further studies are needed to prove or disprove our hypothesis.
引用
收藏
页码:874 / 876
页数:3
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