Stress responses: Translational control perks up

被引：24

作者：

Silverman, RH ^{[1
]}

Williams, BRG ^{[1
]}

机构：

[1] Cleveland Clin Fdn, Lerner Res Inst, Dept Canc Biol, Cleveland, OH 44195 USA

来源：

NATURE | 1999年 / 397卷 / 6716期

关键词：

D O I：

10.1038/16586

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A cell's response to stress is often linked to protein synthesis and folding. These responses must have been conserved through evolution — otherwise, how would multicellular organisms ever have arisen? An evolutionary link has now been found in the form of a newly cloned mammalian stress-response protein called PERK. This protein has features of two gene products that are involved in the stress response in yeast.

引用

页码：208 / +

页数：3

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