Biomaterials for the central nervous system

被引：166

作者：

Zhong, Yinghui ^{[1
]}

Bellamkonda, Ravi V. ^{[1
]}

机构：

[1] Emory Univ, Georgia Inst Technol, Wallace H Coulter Dept Biomed Engn, Lab Neuroengn, Atlanta, GA 30332 USA

来源：

JOURNAL OF THE ROYAL SOCIETY INTERFACE | 2008年 / 5卷 / 26期

关键词：

biomaterials; nerve repair; neural prosthetics;

D O I：

10.1098/rsif.2008.0071

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Biomaterials are widely used to help treat neurological disorders and/or improve functional recovery in the central nervous system (CNS). This article reviews the application of biomaterials in (i) shunting systems for hydrocephalus, (ii) cortical neural prosthetics, (iii) drug delivery in the CNS, (iv) hydrogel scaffolds for CNS repair, and ( v) neural stem cell encapsulation for neurotrauma. The biological and material requirements for the biomaterials in these applications are discussed. The difficulties that the biomaterials might face in each application and the possible solutions are also reviewed in this article.

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页码：957 / 975

页数：19

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