CHADS2 and CHA2DS2-VASc Scores in the Prediction of Clinical Outcomes in Patients With Atrial Fibrillation After Catheter Ablation

被引：146

作者：

Chao, Tze-Fan ^{[1
,2
,3
]}

Lin, Yenn-Jiang ^{[1
,2
,3
]}

Tsao, Hsuan-Ming ^{[2
,3
,7
]}

Tsai, Chin-Feng ^{[8
]}

Lin, Wei-Shiang ^{[4
,5
]}

Chang, Shih-Lin ^{[1
,2
,3
]}

Lo, Li-Wei ^{[1
,2
,3
]}

Hu, Yu-Feng ^{[1
,2
,3
]}

Tuan, Ta-Chuan ^{[1
,2
,3
]}

Suenari, Kazuyoshi ^{[1
,9
]}

Li, Cheng-Hung ^{[1
,2
,3
]}

Hartono, Beny ^{[1
]}

Chang, Hung-Yu ^{[6
]}

Ambrose, Kibos ^{[1
]}

Wu, Tsu-Juey ^{[2
,3
,8
]}

Chen, Shih-Ann ^{[1
,2
,3
]}

机构：

[1] Taipei Vet Gen Hosp, Dept Med, Div Cardiol, Taipei, Taiwan

[2] Natl Yang Ming Univ, Inst Clin Med, Taipei 112, Taiwan

[3] Natl Yang Ming Univ, Cardiovasc Res Ctr, Taipei 112, Taiwan

[4] Natl Def Med Ctr, Dept Internal Med, Div Cardiol, Taipei, Taiwan

[5] Tri Serv Gen Hosp, Taipei, Taiwan

[6] Cheng Hsin Gen Hosp, Div Cardiol, Dept Med, Taipei, Taiwan

[7] Natl Yang Ming Univ Hosp, Div Cardiol, Ilan, Taiwan

[8] Chung Shan Med Univ, Sch Med, Taichung, Taiwan

[9] Hiroshima Univ, Grad Sch Biomed Sci, Dept Cardiovasc Med, Hiroshima, Japan

来源：

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | 2011年 / 58卷 / 23期

关键词：

atrial fibrillation; catheter ablation; CHADS(2) score y; CHA(2)DS(2)-VASc score; STROKE; RISK;

D O I：

10.1016/j.jacc.2011.08.045

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objectives This study aimed to evaluate whether CHADS(2) and CHA(2)DS(2)-VASc scores are useful for risk stratification in patients after catheter ablation of atrial fibrillation (AF). Background AF is associated with increased risk of cardiovascular events. However, limited data are available on the predictors of adverse events in patients with AF after catheter ablation. Methods A total of 565 patients with AF who underwent catheter ablation were enrolled in the study. The clinical end-point was occurrence of thromboembolic events (ischemic stroke, transient ischemic attack, peripheral embolism, or pulmonary embolisms) or death during follow-up after catheter ablation. Results During a follow-up of 39.2 +/- 22.6 months, 27 patients (4.8%) experienced adverse events. Both the CHADS(2) and CHA(2)DS(2)-VASc scores were useful predictors of events in separate multivariate models. The areas under the receiver-operator characteristic curves based on the CHADS(2) and CHA(2)DS(2)-VASc scores in predicting events were 0.785 and 0.830, respectively. Although the difference did not reach statistical significance (p = 0.116), the CHA(2)DS(2)-VASc score could be used to further stratify the patients with CHADS2 scores of 0 or 1 into 2 groups with different event rates (7.1% vs. 1.1%, p = 0.003) at a cutoff value of 2. Conclusions The CHADS2 and CHA(2)DS(2)-VASc scores are useful predictors of adverse events after catheter ablation of AF. (J Am Coll Cardiol 2011;58:2380-5) (C) 2011 by the American College of Cardiology Foundation

引用

页码：2380 / 2385

页数：6

共 6 条

[1] Patients Treated with Catheter Ablation for Atrial Fibrillation Have Long-Term Rates of Death, Stroke, and Dementia Similar to Patients Without Atrial Fibrillation [J].