Methicillin resistant Staphylococcus aureus in the critically ill

被引:67
作者
Hardy, KJ
Hawkey, PM
Gao, F
Oppenheim, BA
机构
[1] Heartlands Hosp, Hlth Protect Agcy, W Midlands Publ Hlth Lab, Birmingham B9 5SS, W Midlands, England
[2] Univ Birmingham, Sch Med, Dept Infect & Immun, Birmingham B15 2TT, W Midlands, England
[3] Heartlands Hosp, Intens Care Unit, Birmingham B9 5SS, W Midlands, England
关键词
complications; infections; methicillin resistant Staphylococcus aureus (MRSA); epidemiology; intensive care;
D O I
10.1093/bja/aeh008
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Methicillin resistant Staphylococcus aureus (MRSA) is endemic within many hospitals worldwide. Critically ill patients on intensive care units have increased risk factors making them especially prone to nosocomially acquired infections. This review addresses the current situation regarding the evolution of MRSA and the techniques for identifying and epidemiologically typing it. It discusses specific risk factors, the morbidity and mortality associated with critically ill patients, and possibilities for future antibiotic treatments.
引用
收藏
页码:121 / 130
页数:10
相关论文
共 94 条
[1]   An enzyme from bacteria able to destroy penicillin [J].
Abraham, EP ;
Chain, E .
NATURE, 1940, 146 :837-837
[2]  
[Anonymous], 2002, MMWR MORB MORTAL WKL, V51, P565
[3]  
Asensio A, 1996, INFECT CONT HOSP EP, V17, P20
[4]   A new UK strain of epidemic methicillin-resistant Staphylococcus aureus (EMRSA-17) resistant to multiple antibiotics [J].
Aucken, HM ;
Ganner, M ;
Murchan, S ;
Cookson, BD ;
Johnson, AP .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2002, 50 (02) :171-175
[6]   An epidemiological survey of methicillin-resistant Staphylococcus aureus in a tertiary referral hospital [J].
Barakate, MS ;
Yang, YX ;
Foo, SH ;
Vickery, AM ;
Sharp, CA ;
Fowler, LD ;
Harris, JP ;
West, RH ;
Macleod, C ;
Benn, RA .
JOURNAL OF HOSPITAL INFECTION, 2000, 44 (01) :19-26
[7]   AN EPIDEMIOLOGIC-STUDY ASSESSING THE RELATIVE IMPORTANCE OF AIRBORNE AND DIRECT CONTACT TRANSMISSION OF MICROORGANISMS IN A MEDICAL INTENSIVE-CARE UNIT [J].
BAUER, TM ;
OFNER, E ;
JUST, HM ;
JUST, H ;
DASCHNER, FD .
JOURNAL OF HOSPITAL INFECTION, 1990, 15 (04) :301-309
[8]   Outcome and attributable mortality in critically ill patients with bacteremia involving methicillin-susceptible and methicillin-resistant Staphylococcus aureus [J].
Blot, SI ;
Vandewoude, KH ;
Hoste, EA ;
Colardyn, FA .
ARCHIVES OF INTERNAL MEDICINE, 2002, 162 (19) :2229-2235
[9]  
Boyce JM, 1997, INFECT CONT HOSP EP, V18, P622
[10]  
*CDC, 2002, MMWR-MORBID MORTAL W, V51, P902