Friedel-Crafts acylation of anisole with acetic anhydride over silica-supported heteropolyphosphotungstic acid (HPW/SiO2)

被引：71

作者：

Cardoso, LAM

Alves, W

Gonzaga, ARE

Aguiar, LMG

Andrade, HMC

机构：

[1] Univ Fed Bahia, Inst Quim, Dept Quim Geral & Inorgan, BR-40170280 Salvador, BA, Brazil

[2] Univ Fed Bahia, Inst Quim, Dept Quim Organ, BR-40170280 Salvador, BA, Brazil

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2004年 / 209卷 / 1-2期

关键词：

Friedel-Crafts acylation; methoxyacetophenones; heteropolyacids; acid anhydride; anisole;

D O I：

10.1016/j.molcata.2003.08.022

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Methoxyacetophenones were synthesized through Friedel-Crafts acylation of anisole with acetic anhydride using a silica-supported heteropolyphosphotungstic acid (HPW) catalyst. High conversions and very high p-selectivity were attained in the temperature range of 61-110degreesC. Nevertheless, the catalyst seemed to deactivate after half an hour at 61 and 83 degreesC, mainly due to strong but reversible adsorption of products. Cleaning the spent catalyst recovered the activity, indicating that it was stable under the experimental conditions and that the active HPW was not fairly leached from the silica support. In spite of this, the slower but progressive coking deactivated the catalyst. (C) 2003 Elsevier B.V. All rights reserved.

引用

页码：189 / 197

页数：9

共 18 条

[1] Supported heteropolyacid (HPW) catalysts for the continuous alkylation of isobutane with 2-butene: The benefit of using MCM-41 with larger pore diameters [J].