The Economics of Sepsis

被引：72

作者：

Chalupka, Andrew N.

Talmor, Daniel ^{[1
,2
]}

机构：

[1] Beth Israel Deaconess Med Ctr, Dept Anesthesia Crit Care & Pain Med, Boston, MA 02215 USA

[2] Harvard Univ, Sch Med, Dept Anesthesia, Boston, MA 02115 USA

来源：

CRITICAL CARE CLINICS | 2012年 / 28卷 / 01期

关键词：

Sepsis; Bloodstream infection; Economics; Costs; Cost-effectiveness; INTENSIVE-CARE UNITS; ACTIVATED PROTEIN-C; BLOOD-STREAM INFECTION; HOSPITAL-ACQUIRED BACTEREMIA; CENTRAL VENOUS CATHETERS; COST-EFFECTIVENESS; METHICILLIN-RESISTANT; NOSOCOMIAL INFECTIONS; ATTRIBUTABLE COST; SURVIVING SEPSIS;

D O I：

10.1016/j.ccc.2011.09.003

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Sepsis, severe sepsis, and septic shock impose a growing economic burden on health care systems globally. This article first describes the epidemiology of sepsis within the United States and internationally. It then reviews costs associated with sepsis and its management in the United States and internationally, including general cost sources in intensive care, direct costs of sepsis, and indirect costs of the burden of illness imposed by sepsis. Finally, it examines the cost-effectiveness of sepsis interventions, focusing on formal cost-effectiveness analyses of nosocomial sepsis prevention strategies, drotrecogin alfa (activated), and integrated sepsis protocols.

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收藏

页码：57 / +

页数：21

相关论文

共 100 条

[1] Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death [J].

Abraham, E ;

Laterre, P ;

Garg, R ;

Levy, H ;

Talwar, D ;

Trzaskoma, BL ;

Francois, B ;

Guy, JS ;

Bruckmann, M ;

Rea-Neto, A ;

Rossaint, R ;

Perrotin, D ;

Sablotzki, A ;

Arkins, N ;

Utterback, BG ;

Macias, WL .

NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (13) :1332-1341

[2] Critical Care 1 Critical care and the global burden of critical illness in adults [J].

Adhikari, Neill K. J. ;

Fowler, Robert A. ;

Bhagwanjee, Satish ;

Rubenfeld, Gordon D. .

LANCET, 2010, 376 (9749) :1339-1346

[3] Epidemiology of sepsis and infection in ICU patients from an international multicentre cohort study [J].

Alberti, C ;

Brun-Buisson, C ;

Burchardi, H ;

Martin, C ;

Goodman, S ;

Artigas, A ;

Sicignano, A ;

Palazzo, M ;

Moreno, R ;

Boulmé, R ;

Lepage, E ;

Le Gall, JR .

INTENSIVE CARE MEDICINE, 2002, 28 (02) :108-121

[4] Epidemiology of sepsis in the Valencian Community (Spain), 1995-2004 [J].

Andreu Ballester, Juan Carlos ;

Ballester, Ferran ;

Gonzalez Sanchez, Antonio ;

Almela Quilis, Amadeo ;

Colomer Rubio, Enrique ;

Penarroja Otero, Carlos .

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2008, 29 (07) :630-634

[5] Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care [J].

Angus, DC ;

Linde-Zwirble, WT ;

Lidicker, J ;

Clermont, G ;

Carcillo, J ;

Pinsky, MR .

CRITICAL CARE MEDICINE, 2001, 29 (07) :1303-1310

[6] Cost-effectiveness of drotrecogin alfa (activated) in the treatment of severe sepsis [J].

Angus, DC ;

Linde-Zwirble, WT ;

Clermont, G ;

Ball, DE ;

Basson, BR ;

Ely, EW ;

Laterre, PF ;

Vincent, JL ;

Bernard, G ;

van Hout, B .

CRITICAL CARE MEDICINE, 2003, 31 (01) :1-11

[7]

[Anonymous], 1996, COST EFFECTIVENESS H, DOI DOI 10.1093/OSO/9780195108248.001.0001

[8]

[Anonymous], COCHRANE DATABASE SY

[9] Nationwide survey on resource availability for implementing current sepsis guidelines in Mongolia [J].

Bataar, Otgon ;

Lundeg, Ganbold ;

Tsenddorj, Ganbat ;

Jochberger, Stefan ;

Grander, Wilhelm ;

Baelani, Inipavudu ;

Wilson, Iain ;

Baker, Tim ;

Duenser, Martin W. .

BULLETIN OF THE WORLD HEALTH ORGANIZATION, 2010, 88 (11) :839-846

[10] Resource utilization among patients with sepsis syndrome [J].

Bates, DW ;

Yu, T ;

Black, E ;

Sands, KE ;

Schwartz, JS ;

Hibberd, PL ;

Graman, PS ;

Lanken, PN ;

Kahn, KL ;

Snydman, DR ;

Parsonnet, J ;

Moore, R ;

Platt, R .

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2003, 24 (01) :62-70

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