Active internalization of the Penicillium chrysogenum antifungal protein PAF in sensitive aspergilli

被引：46

作者：

Oberparleiter, C

Kaiserer, L

Haas, H

Ladurner, P

Andratsch, M

Marx, F

机构：

[1] Univ Innsbruck, Dept Mol Biol, A-6020 Innsbruck, Austria

[2] Univ Innsbruck, Inst Zool & Limnol, A-6020 Innsbruck, Austria

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2003年 / 47卷 / 11期

关键词：

D O I：

10.1128/AAC.47.11.3598-3601.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The Penicillium chrysogenum antifungal protein PAF inhibits the growth of various filamentous fungi. In this study, PAF was found to localize to the cytoplasm of sensitive aspergilli by indirect immunofluorescence staining. The internalization process required active metabolism and ATP and was prevented by latrunculin B, suggesting an endocytotic mechanism.

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页码：3598 / 3601

页数：4

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