Telomeres II

被引：12

作者：

Baird, Duncan M. ^{[1
]}

机构：

[1] Cardiff Univ, Dept Pathol, Cardiff CF14 4XN, S Glam, Wales

来源：

EXPERIMENTAL GERONTOLOGY | 2008年 / 43卷 / 01期

关键词：

telomere; telomerase; ageing; stem cells; senescence;

D O I：

10.1016/j.exger.2007.10.002

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

The extent and potential significance of telomere erosion, as a function of age in human tissues, is becoming increasingly apparent. In this, the second yearly review on telomeres and ageing, I review a small selection of papers published between July 2006 and June 2007. This includes experimental evidence from mouse models concerning the mechanism by which telomere dysfunction could compromise tissue homeostasis, more evidence for telomere loss as a function of age, associations of telomere length with age-related disease and some new information concerning the inheritance of telomere length. (C) 2007 Elsevier Inc. All rights reserved.

引用

页码：15 / 19

页数：5

共 34 条

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