Epidemiology of nasopharyngeal carriage of Neisseria meningitidis in healthy Dutch children

被引：28

作者：

Bogaert, D

Hermans, PWM

Boelens, H

Sluijter, M

Luijendijk, A

Rümke, HC

Koppen, S

van Belkum, A

de Groot, R

Verbrugh, HA

机构：

[1] Sophia Childrens Univ Hosp, Erasmus Med Ctr, Dept Pediat, Rotterdam, Netherlands

[2] Erasmus Univ, Erasmus Med Ctr, Dept Med Microbiol & Infect Dis, Rotterdam, Netherlands

来源：

CLINICAL INFECTIOUS DISEASES | 2005年 / 40卷 / 06期

关键词：

D O I：

10.1086/428351

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We investigated the prevalence and determinants of nasopharyngeal carriage of Neisseria meningitidis in 3200 healthy children aged 1 - 19 years. The incidence of meningococcal carriage was, on average, 1.5%. Peak incidences were seen at age 1 year and after age 15 years. The independent determinants of meningococcal carriage included age, regular visits to youth clubs ( odds ratio [ OR], 2.2) and discotheques ( OR, 4.3), and pneumococcal carriage ( OR, 4.1).

引用

收藏

页码：899 / 902

页数：4

相关论文

共 19 条

[1] Asymtomatic carriage of Neisseria meningitidis and Neisseria lactamica in relation to Streptococcus pneumoniae and Haemophilus influenzae colonization in healthy children:: Apropos of 1400 children sampled [J].

Bakir, M ;

Yagci, A ;

Ulger, N ;

Akbenlioglu, C ;

Ilki, A ;

Soyletir, G .

EUROPEAN JOURNAL OF EPIDEMIOLOGY, 2001, 17 (11) :1015-1018

[2] Streptococcus pneumoniae colonisation:: the key to pneumococcal disease [J].

Bogaert, D ;

de Groot, R ;

Hermans, PWM .

LANCET INFECTIOUS DISEASES, 2004, 4 (03) :144-154

[3] Colonisation by Streptococcus pneumoniae and Staphylococcus aureus in healthy children [J].

Bogaert, D ;

van Belkum, A ;

Sluijter, M ;

Luijendijk, A ;

de Groot, R ;

Rümke, HC ;

Verbrugh, HA ;

Hermans, PWM .

LANCET, 2004, 363 (9424) :1871-1872

[4] THE STONEHOUSE SURVEY - NASOPHARYNGEAL CARRIAGE OF MENINGOCOCCI AND NEISSERIA-LACTAMICA [J].

CARTWRIGHT, KAV ;

STUART, JM ;

JONES, DM ;

NOAH, ND .

EPIDEMIOLOGY AND INFECTION, 1987, 99 (03) :591-601

[5] Changes in frequency and pathogens causing acute otitis media in 1995-2003 [J].

Casey, JR ;

Pichichero, ME .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2004, 23 (09) :824-828

[6] Meningococcal carriage in relation to an outbreak of invasive disease due to Neisseria meningitidis serogroup C in the Netherlands [J].

Conyn-van Spaendonck, MAE ;

Reintjes, R ;

Spanjaard, L ;

van Kregten, E ;

Kraaijeveld, AG ;

Jacobs, PHA .

JOURNAL OF INFECTION, 1999, 39 (01) :42-48

[7] Improved rate of isolation of Neisseria meningitidis by direct plating of pharyngeal swabs [J].

Cunningham, R ;

Matthews, R ;

Lewendon, G ;

Harrison, S ;

Stuart, JM .

JOURNAL OF CLINICAL MICROBIOLOGY, 2001, 39 (12) :4575-4576

[8]

de Greeff S C, 2003, Ned Tijdschr Geneeskd, V147, P1132

[9] Prevalence of Neisseria meningitidis carriers in the school population of Catalonia, Spain [J].

Domínguez, A ;

Cardeñosa, N ;

Izquierdo, C ;

Sánchez, F ;

Margall, N ;

Vázquez, JA ;

Salleras, L .

EPIDEMIOLOGY AND INFECTION, 2001, 127 (03) :425-433

[10] Detection of meningococcal carriage by culture and PCR of throat swabs and mouth gargles [J].

Jordens, JZ ;

Williams, JN ;

Jones, GR ;

Heckels, JE .

JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (01) :75-79