QSAR of flavylium salts as inhibitors of xanthine oxidase

被引：5

作者：

Amic, D

Davidovic-Amic, D

Beslo, D

Lucic, B

Trinajstic, N

机构：

[1] Josip Juraj Strossmayer Univ, Fac Agr, HR-31001 Osijek, Croatia

[2] Rudjer Boskovic Inst, HR-10001 Zagreb, Croatia

来源：

JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES | 1998年 / 38卷 / 05期

关键词：

D O I：

10.1021/ci980002r

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A simple QSAR model of xanthine oxidase (XO) inhibitory flavylium salts, which enables prediction of the inhibitory potency of anthocyanidins as a function of their molecular properties, has been developed. The results obtained in the present work help to understand which of the several tautomeric anhydrobase species present in nearly neutral solution are mainly responsible for the inhibition of XO.

引用

页码：815 / 818

页数：4

共 19 条

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